8UOA
Structure of the synaptic vesicle protein 2A Luminal domain in complex with a nanobody
Summary for 8UOA
Entry DOI | 10.2210/pdb8uoa/pdb |
EMDB information | 42432 |
Descriptor | Synaptic vesicle glycoprotein 2A, Nanobody, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | synaptic vesicle, slc22, inhibitor, nanobody, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 92493.63 |
Authors | Mittal, A.,Martin, M.F.,Levin, E.,Adams, C.,Yang, M.,Ledecq, M.,Horanyi, P.S.,Coleman, J.A. (deposition date: 2023-10-19, release date: 2024-05-22, Last modification date: 2024-06-26) |
Primary citation | Mittal, A.,Martin, M.F.,Levin, E.J.,Adams, C.,Yang, M.,Provins, L.,Hall, A.,Procter, M.,Ledecq, M.,Hillisch, A.,Wolff, C.,Gillard, M.,Horanyi, P.S.,Coleman, J.A. Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38898101DOI: 10.1038/s41594-024-01335-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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