8SL1
Cryo-EM structure of PAPP-A2
Summary for 8SL1
Entry DOI | 10.2210/pdb8sl1/pdb |
EMDB information | 40571 |
Descriptor | Pappalysin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (6 entities in total) |
Functional Keywords | protease, zinc binding, growth factor signaling, peptide binding, hydrolase, peptide binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 175050.94 |
Authors | Judge, R.A.,Stoll, V.S.,Eaton, D.,Hao, Q.,Bratkowski, M.A. (deposition date: 2023-04-20, release date: 2023-11-08, Last modification date: 2024-05-01) |
Primary citation | Sridar, J.,Mafi, A.,Judge, R.A.,Xu, J.,Kong, K.A.,Wang, J.C.K.,Stoll, V.S.,Koukos, G.,Simon, R.J.,Eaton, D.,Bratkowski, M.,Hao, Q. Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition. Commun Chem, 6:234-234, 2023 Cited by PubMed: 37898658DOI: 10.1038/s42004-023-01032-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.13 Å) |
Structure validation
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