8SK7
Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43)
Summary for 8SK7
Entry DOI | 10.2210/pdb8sk7/pdb |
EMDB information | 40557 |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin, HA_20 minibinder (RFdiffusion-designed), ... (6 entities in total) |
Functional Keywords | flu, influenza, hemagglutinin, ha, iowa43, ha_20, de novo protein, minibinder, binder, designed protein, fusion protein, glycoprotein, de novo protein-viral protein complex, de novo protein/viral protein |
Biological source | Influenza A virus More |
Total number of polymer chains | 9 |
Total formula weight | 215503.28 |
Authors | Borst, A.J.,Bennett, N.R. (deposition date: 2023-04-18, release date: 2023-06-14, Last modification date: 2023-09-13) |
Primary citation | Watson, J.L.,Juergens, D.,Bennett, N.R.,Trippe, B.L.,Yim, J.,Eisenach, H.E.,Ahern, W.,Borst, A.J.,Ragotte, R.J.,Milles, L.F.,Wicky, B.I.M.,Hanikel, N.,Pellock, S.J.,Courbet, A.,Sheffler, W.,Wang, J.,Venkatesh, P.,Sappington, I.,Torres, S.V.,Lauko, A.,De Bortoli, V.,Mathieu, E.,Ovchinnikov, S.,Barzilay, R.,Jaakkola, T.S.,DiMaio, F.,Baek, M.,Baker, D. De novo design of protein structure and function with RFdiffusion. Nature, 620:1089-1100, 2023 Cited by PubMed: 37433327DOI: 10.1038/s41586-023-06415-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.93 Å) |
Structure validation
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