8S7C
Ternary Complex of Cachd1, FZD5 and LRP6
Summary for 8S7C
Entry DOI | 10.2210/pdb8s7c/pdb |
Descriptor | VWFA and cache domain-containing protein 1, Frizzled-5, Low-density lipoprotein receptor-related protein 6, ... (5 entities in total) |
Functional Keywords | cachd1 frizzled-5 lrp6, signaling protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 9 |
Total formula weight | 637942.28 |
Authors | Zhao, Y.,Ren, J.,Jones, E.Y. (deposition date: 2024-02-29, release date: 2024-04-24, Last modification date: 2024-05-15) |
Primary citation | Powell, G.T.,Faro, A.,Zhao, Y.,Stickney, H.,Novellasdemunt, L.,Henriques, P.,Gestri, G.,Redhouse White, E.,Ren, J.,Lu, W.,Young, R.M.,Hawkins, T.A.,Cavodeassi, F.,Schwarz, Q.,Dreosti, E.,Raible, D.W.,Li, V.S.W.,Wright, G.J.,Jones, E.Y.,Wilson, S.W. Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain. Science, 384:573-579, 2024 Cited by PubMed: 38696577DOI: 10.1126/science.ade6970 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.7 Å) |
Structure validation
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