8PVB
Structure of GABAAR determined by cryoEM at 100 keV
Summary for 8PVB
Entry DOI | 10.2210/pdb8pvb/pdb |
EMDB information | 17960 |
Descriptor | Gamma-aminobutyric acid receptor subunit beta-3, Megabody Mb25, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | pentameric ligand-gated ion channel, neurotrasmitter receptor, gaba(a) receptor, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 104602.05 |
Authors | McMullan, G.,Naydenova, K.,Mihaylov, D.,Peet, M.J.,Wilson, H.,Yamashita, K.,Dickerson, J.L.,Chen, S.,Cannone, G.,Lee, Y.,Hutchings, K.A.,Gittins, O.,Sobhy, M.,Wells, T.,El-Gomati, M.M.,Dalby, J.,Meffert, M.,Schulze-Briese, C.,Henderson, R.,Russo, C.J. (deposition date: 2023-07-17, release date: 2023-11-29, Last modification date: 2024-01-31) |
Primary citation | McMullan, G.,Naydenova, K.,Mihaylov, D.,Yamashita, K.,Peet, M.J.,Wilson, H.,Dickerson, J.L.,Chen, S.,Cannone, G.,Lee, Y.,Hutchings, K.A.,Gittins, O.,Sobhy, M.A.,Wells, T.,El-Gomati, M.M.,Dalby, J.,Meffert, M.,Schulze-Briese, C.,Henderson, R.,Russo, C.J. Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120:e2312905120-e2312905120, 2023 Cited by PubMed: 38011573DOI: 10.1073/pnas.2312905120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
Download full validation report