8PE2
Crystal structure of Gel4 in complex with Nanobody 3
Summary for 8PE2
Entry DOI | 10.2210/pdb8pe2/pdb |
Descriptor | 1,3-beta-glucanosyltransferase, Nanobody 3, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | transglycosylase, b-1, 3-glucan, nanobodies, fungal diseases, transferase |
Biological source | Aspergillus fumigatus More |
Total number of polymer chains | 2 |
Total formula weight | 64602.83 |
Authors | Macias-Leon, J.,Redrado-Hernandez, S.,Castro-Lopez, J.,Sanz, A.B.,Arias, M.,Farkas, V.,Vincke, C.,Muyldermans, S.,Pardo, J.,Arroyo, J.,Galvez, E.,Hurtado-Guerrero, R. (deposition date: 2023-06-13, release date: 2024-06-19, Last modification date: 2024-08-21) |
Primary citation | Redrado-Hernandez, S.,Macias-Leon, J.,Castro-Lopez, J.,Belen Sanz, A.,Dolader, E.,Arias, M.,Gonzalez-Ramirez, A.M.,Sanchez-Navarro, D.,Petryk, Y.,Farkas, V.,Vincke, C.,Muyldermans, S.,Garcia-Barbazan, I.,Del Agua, C.,Zaragoza, O.,Arroyo, J.,Pardo, J.,Galvez, E.M.,Hurtado-Guerrero, R. Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 63:e202405823-e202405823, 2024 Cited by PubMed: 38856634DOI: 10.1002/anie.202405823 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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