8P0L
Crystal structure of human O-GlcNAcase in complex with an S-linked CKII peptide
Summary for 8P0L
Entry DOI | 10.2210/pdb8p0l/pdb |
Descriptor | Protein O-GlcNAcase, CYSTEINE, SERINE, ... (5 entities in total) |
Functional Keywords | carbohydrate, s-glcnac, gh84, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 206489.27 |
Authors | Males, A.,Davies, G.J.,Calvelo, M.,Alteen, M.G.,Vocadlo, D.J.,Rovira, C. (deposition date: 2023-05-10, release date: 2023-11-29) |
Primary citation | Calvelo, M.,Males, A.,Alteen, M.G.,Willems, L.I.,Vocadlo, D.J.,Davies, G.J.,Rovira, C. Human O -GlcNAcase Uses a Preactivated Boat-skew Substrate Conformation for Catalysis. Evidence from X-ray Crystallography and QM/MM Metadynamics. Acs Catalysis, 13:13672-13678, 2023 Cited by PubMed: 37969138DOI: 10.1021/acscatal.3c02378 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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