8OS2
Structure of the human LYVE-1 (lymphatic vessel endothelial receptor-1) hyaluronan binding domain in an unliganded state
Summary for 8OS2
Entry DOI | 10.2210/pdb8os2/pdb |
Related | 8ORX |
Descriptor | Lymphatic vessel endothelial hyaluronic acid receptor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (4 entities in total) |
Functional Keywords | hyaluronan binding, cell migration, lymphatic system, cell adhesion |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 16729.32 |
Authors | Ni, T.,Bannerji, S.,Jackson, D.J.,Gilbert, R.J.C. (deposition date: 2023-04-17, release date: 2024-07-31) |
Primary citation | Bano, F.,Bannerji, S.,Ni, T.,Green, D.E.,DeAngelis, P.L.,Paci, E.,Lepsik, M.,Jackson, D.J.,Gilbert, R.J.C. A novel sliding interaction with hyaluronan underlies the mode of action of LYVE-1, the receptor for leucocyte entry and trafficking in the lymphatics To be published, |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
Download full validation report