8OK7
Variant Surface Glycoprotein VSG558 NTD
Summary for 8OK7
Entry DOI | 10.2210/pdb8ok7/pdb |
Descriptor | Variant surface glycoprotein 558, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | variant surface glycoprotein suramin trypanosomiasis drug resistance glycosylation, membrane protein |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 4 |
Total formula weight | 188118.14 |
Authors | Zeelen, J.P.,Stebbins, C.E.,van Straaten, M.,Zhong, J. (deposition date: 2023-03-27, release date: 2023-09-13) |
Primary citation | Dakovic, S.,Zeelen, J.P.,Gkeka, A.,Chandra, M.,van Straaten, M.,Foti, K.,Zhong, J.,Vlachou, E.P.,Aresta-Branco, F.,Verdi, J.P.,Papavasiliou, F.N.,Stebbins, C.E. A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17:e0011621-e0011621, 2023 Cited by PubMed: 37656766DOI: 10.1371/journal.pntd.0011621 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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