8K5H
Structure of the SARS-CoV-2 BA.1 spike with UT28-RD
Summary for 8K5H
Entry DOI | 10.2210/pdb8k5h/pdb |
EMDB information | 36906 |
Descriptor | Spike glycoprotein, UT28K-RD Fab heavy chain, UT28K-RD Fab light chain, ... (5 entities in total) |
Functional Keywords | sars-cov-2, antibody, spike protein, structural protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV,SARS-CoV-2) More |
Total number of polymer chains | 5 |
Total formula weight | 463435.17 |
Authors | Chen, L.,Kita, S.,Anraku, Y.,Maenaka, K. (deposition date: 2023-07-21, release date: 2023-12-27, Last modification date: 2024-07-10) |
Primary citation | Ozawa, T.,Ikeda, Y.,Chen, L.,Suzuki, R.,Hoshino, A.,Noguchi, A.,Kita, S.,Anraku, Y.,Igarashi, E.,Saga, Y.,Inasaki, N.,Taminishi, S.,Sasaki, J.,Kirita, Y.,Fukuhara, H.,Maenaka, K.,Hashiguchi, T.,Fukuhara, T.,Hirabayashi, K.,Tani, H.,Kishi, H.,Niimi, H. Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1. Structure, 32:263-272.e7, 2024 Cited by PubMed: 38228146DOI: 10.1016/j.str.2023.12.013 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
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