8J6F
Cryo-EM structure of the Tocilizumab Fab/IL-6R complex
Summary for 8J6F
Entry DOI | 10.2210/pdb8j6f/pdb |
EMDB information | 36003 |
Descriptor | Heavy chain of Tocilizumab Fab, Light chain of Tocilizumab Fab, Interleukin-6 receptor subunit alpha, ... (5 entities in total) |
Functional Keywords | antibody, il-6r, structural protein, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 89305.16 |
Authors | |
Primary citation | She, J.,Wang, M.X. Cryo-EM structures of tocilizumab and sarilumab Fabs in complex with IL-6R To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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