8IHF
Cryo-EM structure of HCA2-Gi complex with MK6892
Summary for 8IHF
Entry DOI | 10.2210/pdb8ihf/pdb |
EMDB information | 35443 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total) |
Functional Keywords | gpcr, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 191902.34 |
Authors | Suzuki, S.,Nishikawa, K.,Suzuki, H.,Fujiyoshi, Y. (deposition date: 2023-02-22, release date: 2023-08-30, Last modification date: 2023-12-06) |
Primary citation | Suzuki, S.,Tanaka, K.,Nishikawa, K.,Suzuki, H.,Oshima, A.,Fujiyoshi, Y. Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding. Nat Commun, 14:5899-5899, 2023 Cited by PubMed: 37736747DOI: 10.1038/s41467-023-41650-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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