8HLP
Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo)
Summary for 8HLP
Entry DOI | 10.2210/pdb8hlp/pdb |
EMDB information | 34880 |
Descriptor | Voltage-dependent L-type calcium channel subunit alpha, Voltage-dependent calcium channel subunit alpha-2/delta-1, Isoform 2c of Voltage-dependent L-type calcium channel subunit beta-2, ... (7 entities in total) |
Functional Keywords | apo state, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 440817.40 |
Authors | |
Primary citation | Wei, Y.,Yu, Z.,Wang, L.,Li, X.,Li, N.,Bai, Q.,Wang, Y.,Li, R.,Meng, Y.,Xu, H.,Wang, X.,Dong, Y.,Huang, Z.,Zhang, X.C.,Zhao, Y. Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors. Nat Commun, 15:2772-2772, 2024 Cited by PubMed: 38555290DOI: 10.1038/s41467-024-47116-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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