8G4T
Vaccine-elicited human antibody 2C09 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Summary for 8G4T
Entry DOI | 10.2210/pdb8g4t/pdb |
EMDB information | 29731 |
Descriptor | Envelope glycoprotein BG505 DS-SOSIP gp41, Envelope glycoprotein BG505 DS-SOSIP gp120, Fab 2C09 heavy chain, ... (9 entities in total) |
Functional Keywords | antibody-antigen complex vaccine-elicited antibody fusion peptide strain specific, antiviral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 380886.60 |
Authors | Wang, S.,Kwong, P.D. (deposition date: 2023-02-10, release date: 2023-07-12, Last modification date: 2023-07-26) |
Primary citation | Wang, S.,Matassoli, F.,Zhang, B.,Liu, T.,Shen, C.H.,Bylund, T.,Johnston, T.,Henry, A.R.,Teng, I.T.,Tripathi, P.,Becker, J.E.,Changela, A.,Chaudhary, R.,Cheng, C.,Gaudinski, M.,Gorman, J.,Harris, D.R.,Lee, M.,Morano, N.C.,Novik, L.,O'Dell, S.,Olia, A.S.,Parchment, D.K.,Rawi, R.,Roberts-Torres, J.,Stephens, T.,Tsybovsky, Y.,Wang, D.,Van Wazer, D.J.,Zhou, T.,Doria-Rose, N.A.,Koup, R.A.,Shapiro, L.,Douek, D.C.,McDermott, A.B.,Kwong, P.D. HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide. Cell Rep, 42:112755-112755, 2023 Cited by PubMed: 37436899DOI: 10.1016/j.celrep.2023.112755 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.81 Å) |
Structure validation
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