8FL1
Cryo-EM Structure of PG9RSH DU025 Fab in complex with BG505 DS-SOSIP.664
This is a non-PDB format compatible entry.
Summary for 8FL1
Entry DOI | 10.2210/pdb8fl1/pdb |
EMDB information | 29264 |
Descriptor | Envelope glycoprotein gp41, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... (10 entities in total) |
Functional Keywords | cd4, hiv-1, sosip, vaccine, immune system, llama, v2 apex, therapeutic, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 8 |
Total formula weight | 285870.35 |
Authors | Gorman, J.,Kwong, P.D. (deposition date: 2022-12-21, release date: 2023-05-31, Last modification date: 2023-07-26) |
Primary citation | Holt, G.T.,Gorman, J.,Wang, S.,Lowegard, A.U.,Zhang, B.,Liu, T.,Lin, B.C.,Louder, M.K.,Frenkel, M.S.,McKee, K.,O'Dell, S.,Rawi, R.,Shen, C.H.,Doria-Rose, N.A.,Kwong, P.D.,Donald, B.R. Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design. Cell Rep, 42:112711-112711, 2023 Cited by PubMed: 37436900DOI: 10.1016/j.celrep.2023.112711 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.75 Å) |
Structure validation
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