8EPM

Human R-type voltage-gated calcium channel Cav2.3 CH2II-deleted mutant at 3.1 Angstrom resolution

Summary for 8EPM

• Entry DOI: 10.2210/pdb8epm/pdb
• EMDB information: 28530
• Descriptor: Voltage-dependent R-type calcium channel subunit alpha-1E, Voltage-dependent calcium channel subunit alpha-2/delta-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: cav2.3, channels, calcium ion-selective, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 390020.62

Authors

Gao, S.,Yao, X.,Yan, N. (deposition date: 2022-10-06, release date: 2022-12-14, Last modification date: 2023-07-12)

• Primary citation: Yao, X.,Wang, Y.,Wang, Z.,Fan, X.,Wu, D.,Huang, J.,Mueller, A.,Gao, S.,Hu, M.,Robinson, C.V.,Yu, Y.,Gao, S.,Yan, N.; Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments.; Nat Commun, 13:7358-7358, 2022; PubMed: 36446785; DOI: 10.1038/s41467-022-35026-6

Experimental method

ELECTRON MICROSCOPY (3.1 Å)