8EE6
Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs
Summary for 8EE6
Entry DOI | 10.2210/pdb8ee6/pdb |
EMDB information | 28047 |
Descriptor | Phospholipid-transporting ATPase ABCA7, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | abc transporter, lipid transporter, abc exporter, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 251129.56 |
Authors | Alam, A.,Le, L.T.M.,Thompson, J.R. (deposition date: 2022-09-06, release date: 2022-12-21, Last modification date: 2023-02-15) |
Primary citation | Le, L.T.M.,Thompson, J.R.,Dehghani-Ghahnaviyeh, S.,Pant, S.,Dang, P.X.,French, J.B.,Kanikeyo, T.,Tajkhorshid, E.,Alam, A. Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms. Embo J., 42:e111065-e111065, 2023 Cited by PubMed: 36484366DOI: 10.15252/embj.2022111065 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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