8EE5
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E glycoprotein
Summary for 8EE5
Entry DOI | 10.2210/pdb8ee5/pdb |
Descriptor | Envelope protein E, rhMZ119-D antibody heavy chain, rhMZ119-D antibody light chain, ... (4 entities in total) |
Functional Keywords | zikv, zikv-specific, cross-protomer epitopes, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013 More |
Total number of polymer chains | 3 |
Total formula weight | 90508.33 |
Authors | |
Primary citation | Sankhala, R.S.,Dussupt, V.,Donofrio, G.,Gromowski, G.D.,De La Barrera, R.A.,Larocca, R.A.,Mendez-Rivera, L.,Lee, A.,Choe, M.,Zaky, W.,Mantus, G.,Jensen, J.L.,Chen, W.H.,Gohain, N.,Bai, H.,McCracken, M.K.,Mason, R.D.,Leggat, D.,Slike, B.M.,Tran, U.,Jian, N.,Abbink, P.,Peterson, R.,Mendes, E.A.,Freitas de Oliveira Franca, R.,Calvet, G.A.,Bispo de Filippis, A.M.,McDermott, A.,Roederer, M.,Hernandez, M.,Albertus, A.,Davidson, E.,Doranz, B.J.,Rolland, M.,Robb, M.L.,Lynch, R.M.,Barouch, D.H.,Jarman, R.G.,Thomas, S.J.,Modjarrad, K.,Michael, N.L.,Krebs, S.J.,Joyce, M.G. Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42:112942-112942, 2023 Cited by PubMed: 37561630DOI: 10.1016/j.celrep.2023.112942 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.583 Å) |
Structure validation
Download full validation report