8E98
D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in nanodisc - intact conformation
Summary for 8E98
Entry DOI | 10.2210/pdb8e98/pdb |
EMDB information | 27953 27954 27955 27957 27958 27959 27960 27961 |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2C, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | ligand-gated ion channel, ionotropic glutamate receptor, synaptic protein, voltage-gate ion channel, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 387830.69 |
Authors | Chou, T.-H.,Furukawa, H. (deposition date: 2022-08-26, release date: 2022-12-07, Last modification date: 2022-12-14) |
Primary citation | Chou, T.H.,Kang, H.,Simorowski, N.,Traynelis, S.F.,Furukawa, H. Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82:4548-, 2022 Cited by PubMed: 36309015DOI: 10.1016/j.molcel.2022.10.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.75 Å) |
Structure validation
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