8E7M
Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04
Summary for 8E7M
Entry DOI | 10.2210/pdb8e7m/pdb |
EMDB information | 27939 |
Descriptor | Angiotensin-converting enzyme 2, 05B04 Heavy Chain, 05B04 Light Chain, ... (6 entities in total) |
Functional Keywords | ace2, antibody, sars-cov-2, inhibition, antiviral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 122033.32 |
Authors | |
Primary citation | Zhang, F.,Jenkins, J.,de Carvalho, R.V.,Nakandakari-Higa, S.,Chen, T.,Abernathy, M.E.,Nyakatura, E.,Andrew, D.,Lebedeva, I.,Lorenz, I.C.,Hoffmann, H.H.,Rice, C.M.,Victora, G.D.,Barnes, C.O.,Haziioannou, T.,Bieniasz, P.D. Human anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents Biorxiv, 2022 Cited by DOI: 10.1101/2022.08.24.505169PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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