8C7H
Cryo-EM Map of the latTGF-beta 28G11 Fab complex
Summary for 8C7H
Entry DOI | 10.2210/pdb8c7h/pdb |
EMDB information | 16460 |
Descriptor | Transforming growth factor beta-1, Transforming growth factor beta activator LRRC32, 28G11 Fab heavy chain, ... (6 entities in total) |
Functional Keywords | fab-complex, garp, lat-tgf-beta, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 197421.50 |
Authors | Ebenhoch, R.,Nar, H. (deposition date: 2023-01-16, release date: 2023-03-01, Last modification date: 2023-03-29) |
Primary citation | Igney, F.H.,Ebenhoch, R.,Schiele, F.,Nar, H. Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Immunohorizons, 7:200-212, 2023 Cited by PubMed: 36928178DOI: 10.4049/immunohorizons.2200072 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
Download full validation report