8ACI
Structure of ARG-117 Fab in complex with a fragment of complement C2, neutral pH
Summary for 8ACI
Entry DOI | 10.2210/pdb8aci/pdb |
Descriptor | Complement C2b fragment, ARGX-117 Fab heavy chain, nanobody specific for kappa light chain of Fab, ... (9 entities in total) |
Functional Keywords | innate immune system, antibody, complement, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 83164.69 |
Authors | |
Primary citation | Olesen, H.G.,Andersen, G.R. Structure-function analysis of ARGX-117, a calcium- and pH-dependent clinical phase complement C2 blocking antibody To be published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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