7ZUB
Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex
Summary for 7ZUB
Entry DOI | 10.2210/pdb7zub/pdb |
EMDB information | 14971 |
Descriptor | Heat shock protein HSP 90-beta, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... (7 entities in total) |
Functional Keywords | complex, nuclear receptor, chemical pollutants, detoxification, cancer, gene regulation |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 257370.36 |
Authors | Gruszczyk, J.,Savva, C.G.,Lai-Kee-Him, J.,Bous, J.,Ancelin, A.,Kwong, H.S.,Grandvuillemin, L.,Bourguet, W. (deposition date: 2022-05-12, release date: 2022-11-23, Last modification date: 2024-07-24) |
Primary citation | Gruszczyk, J.,Grandvuillemin, L.,Lai-Kee-Him, J.,Paloni, M.,Savva, C.G.,Germain, P.,Grimaldi, M.,Boulahtouf, A.,Kwong, H.S.,Bous, J.,Ancelin, A.,Bechara, C.,Barducci, A.,Balaguer, P.,Bourguet, W. Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13:7010-7010, 2022 Cited by PubMed: 36385050DOI: 10.1038/s41467-022-34773-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.85 Å) |
Structure validation
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