7Z9P
The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic
Summary for 7Z9P
Entry DOI | 10.2210/pdb7z9p/pdb |
Descriptor | DNA (5'-D(P*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G*(RID))-3'), Ridinilazole, SULFATE ION, ... (6 entities in total) |
Functional Keywords | clostridiodes difficile, antibiotic, dna-binding, drug discovery, target identification, dna |
Biological source | synthetic construct (32630) |
Total number of polymer chains | 6 |
Total formula weight | 23845.16 |
Authors | Mason, S.,Leonard, P.M. (deposition date: 2022-03-21, release date: 2023-03-29, Last modification date: 2024-02-07) |
Primary citation | Mason, C.S.,Avis, T.,Hu, C.,Nagalingam, N.,Mudaliar, M.,Coward, C.,Begum, K.,Gajewski, K.,Alam, M.J.,Basseres, E.,Moss, S.,Reich, S.,Duperchy, E.,Fox, K.R.,Garey, K.W.,Powell, D.J. The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. Antimicrob.Agents Chemother., 67:e0156322-e0156322, 2023 Cited by PubMed: 37093023DOI: 10.1128/aac.01563-22 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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