7SF4
M. tb EgtD in complex with imatinib
Summary for 7SF4
Entry DOI | 10.2210/pdb7sf4/pdb |
Descriptor | Histidine N-alpha-methyltransferase, 2-AMINO-4-PYRIDYL-PYRIMIDINE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | ergothioneine biosynthesis pathway, rossmann fold domain, histidine binding site, sam dependent methyltransferase, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 72023.06 |
Authors | Sudasinghe, T.D.,Ronning, D.R. (deposition date: 2021-10-03, release date: 2021-12-01, Last modification date: 2023-10-18) |
Primary citation | Sudasinghe, T.D.,Banco, M.T.,Ronning, D.R. Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production. Sci Rep, 11:22240-22240, 2021 Cited by PubMed: 34782676DOI: 10.1038/s41598-021-01526-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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