7QUO
FimH lectin domain in complex with oligomannose-6
Summary for 7QUO
Entry DOI | 10.2210/pdb7quo/pdb |
Related | 7BHD |
Descriptor | FimH, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ... (5 entities in total) |
Functional Keywords | type-1 fimbriae, escherichia coli, fimh, adhesin, lectin, oligomannose, high-mannose, cell adhesion |
Biological source | Escherichia coli BL21(DE3) |
Total number of polymer chains | 4 |
Total formula weight | 70888.70 |
Authors | Bouckaert, J.,Bourenkov, G.P. (deposition date: 2022-01-18, release date: 2023-02-01, Last modification date: 2024-02-14) |
Primary citation | Krammer, E.M.,Bridot, C.,Serna, S.,Echeverria, B.,Semwal, S.,Roubinet, B.,van Noort, K.,Wilbers, R.H.,Bourenkov, G.,de Ruyck, J.,Landemarre, L.,Reichardt, N.,Bouckaert, J. Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors J.Biol.Chem., 299:104627-, 2023 Cited by DOI: 10.1016/j.jbc.2023.104627PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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