7D7M

Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein

Summary for 7D7M

• Entry DOI: 10.2210/pdb7d7m/pdb
• EMDB information: 30608
• Descriptor: Prostaglandin E2 receptor EP4 subtype,Prostaglandin E2 receptor EP4 subtype, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: prostaglandin e receptor, ep4, gpcr, g protein, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 126590.26

Authors

Nojima, S.,Fujita, Y.,Kimura, T.K.,Nomura, N.,Suno, R.,Morimoto, K.,Yamamoto, M.,Noda, T.,Iwata, S.,Shigematsu, H.,Kobayashi, T. (deposition date: 2020-10-05, release date: 2020-11-18, Last modification date: 2021-03-17)

• Primary citation: Nojima, S.,Fujita, Y.,Kimura, K.T.,Nomura, N.,Suno, R.,Morimoto, K.,Yamamoto, M.,Noda, T.,Iwata, S.,Shigematsu, H.,Kobayashi, T.; Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein.; Structure, 29:252-260.e6, 2021; PubMed: 33264604; DOI: 10.1016/j.str.2020.11.007

Experimental method

ELECTRON MICROSCOPY (3.3 Å)