7D42
Structural basis of tropifexor as a potent and selective agonist for farnesoid X receptor
Summary for 7D42
Entry DOI | 10.2210/pdb7d42/pdb |
Descriptor | Bile acid receptor, Peptide from Nuclear receptor coactivator 2, Tropifexor (3 entities in total) |
Functional Keywords | farnesoid x receptor, tropifexor, nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 31194.58 |
Authors | |
Primary citation | Jiang, L.,Xiao, D.,Li, Y.,Dai, S.,Qu, L.,Chen, X.,Guo, M.,Wei, H.,Chen, Y. Structural basis of tropifexor as a potent and selective agonist of farnesoid X receptor. Biochem.Biophys.Res.Commun., 534:1047-1052, 2021 Cited by PubMed: 33121679DOI: 10.1016/j.bbrc.2020.10.039 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.697 Å) |
Structure validation
Download full validation report