7CT5

S protein of SARS-CoV-2 in complex bound with T-ACE2

Summary for 7CT5

• Entry DOI: 10.2210/pdb7ct5/pdb
• EMDB information: 30460 30461
• Descriptor: Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: s-ecd, ace2, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 674913.50

Authors

Guo, L.,Bi, W.W.,Zhang, Y.Y.,Yan, R.H.,Li, Y.N.,Zhou, Q.,Dang, B.B. (deposition date: 2020-08-18, release date: 2020-11-18, Last modification date: 2021-02-10)

• Primary citation: Guo, L.,Bi, W.,Wang, X.,Xu, W.,Yan, R.,Zhang, Y.,Zhao, K.,Li, Y.,Zhang, M.,Cai, X.,Jiang, S.,Xie, Y.,Zhou, Q.,Lu, L.,Dang, B.; Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.; Cell Res., 31:98-100, 2021; PubMed: 33177651; DOI: 10.1038/s41422-020-00438-w

Experimental method

ELECTRON MICROSCOPY (4 Å)