7YSU
Cryo-EM Structure of FGF23-FGFR3c-aKlotho-HS Quaternary Complex
Summary for 7YSU
Entry DOI | 10.2210/pdb7ysu/pdb |
EMDB information | 34082 |
Descriptor | Klotho, Fibroblast growth factor receptor 3, Fibroblast growth factor 23, ... (6 entities in total) |
Functional Keywords | fgf hormones, fgf receptor, klotho co-receptor, heparan sulfate glycosaminoglycans, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 178606.18 |
Authors | Mohammadi, M.,Chen, L. (deposition date: 2022-08-13, release date: 2023-04-19, Last modification date: 2023-07-05) |
Primary citation | Chen, L.,Fu, L.,Sun, J.,Huang, Z.,Fang, M.,Zinkle, A.,Liu, X.,Lu, J.,Pan, Z.,Wang, Y.,Liang, G.,Li, X.,Chen, G.,Mohammadi, M. Structural basis for FGF hormone signalling. Nature, 618:862-870, 2023 Cited by PubMed: 37286607DOI: 10.1038/s41586-023-06155-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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