7YA0
Cryo-EM structure of hACE2-bound SARS-CoV-2 Omicron spike protein with L371S, P373S and F375S mutations (S-6P-RRAR)
This is a non-PDB format compatible entry.
Summary for 7YA0
Entry DOI | 10.2210/pdb7ya0/pdb |
EMDB information | 33698 |
Descriptor | Spike glycoprotein, Processed angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | sars-cov-2, omicron, spike protein, viral protein, viral protein-hydrolase complex, viral protein/hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 6 |
Total formula weight | 635608.68 |
Authors | Zhao, Z.N.,Xie, Y.F.,Qi, J.X.,Gao, G.F. (deposition date: 2022-06-26, release date: 2022-09-21, Last modification date: 2023-08-02) |
Primary citation | Zhao, Z.,Zhou, J.,Tian, M.,Huang, M.,Liu, S.,Xie, Y.,Han, P.,Bai, C.,Han, P.,Zheng, A.,Fu, L.,Gao, Y.,Peng, Q.,Li, Y.,Chai, Y.,Zhang, Z.,Zhao, X.,Song, H.,Qi, J.,Wang, Q.,Wang, P.,Gao, G.F. Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13:4958-4958, 2022 Cited by PubMed: 36002453DOI: 10.1038/s41467-022-32665-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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