7Y9Z
Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (one-RBD-up state)
Summary for 7Y9Z
Entry DOI | 10.2210/pdb7y9z/pdb |
EMDB information | 33697 |
Descriptor | Spike glycoprotein, Processed angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | omicron, ace2, sars-cov-2, one rbd up, virus, viral protein-hydrolase complex, viral protein/hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 4 |
Total formula weight | 502788.62 |
Authors | |
Primary citation | Zhao, Z.,Zhou, J.,Tian, M.,Huang, M.,Liu, S.,Xie, Y.,Han, P.,Bai, C.,Han, P.,Zheng, A.,Fu, L.,Gao, Y.,Peng, Q.,Li, Y.,Chai, Y.,Zhang, Z.,Zhao, X.,Song, H.,Qi, J.,Wang, Q.,Wang, P.,Gao, G.F. Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13:4958-4958, 2022 Cited by PubMed: 36002453DOI: 10.1038/s41467-022-32665-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.85 Å) |
Structure validation
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