7UWN
Structure of the IL-17A-IL-17RA-IL-17RC ternary complex
Summary for 7UWN
Entry DOI | 10.2210/pdb7uwn/pdb |
EMDB information | 26837 |
Descriptor | Interleukin-17A, Interleukin-17 receptor A, Isoform 5 of Interleukin-17 receptor C, ... (5 entities in total) |
Functional Keywords | receptor complex, il-17a, il-17ra, il-17rc, cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 206733.53 |
Authors | Wilson, S.C.,Caveney, N.A.,Jude, K.M.,Garcia, K.C. (deposition date: 2022-05-03, release date: 2022-07-27, Last modification date: 2022-09-28) |
Primary citation | Wilson, S.C.,Caveney, N.A.,Yen, M.,Pollmann, C.,Xiang, X.,Jude, K.M.,Hafer, M.,Tsutsumi, N.,Piehler, J.,Garcia, K.C. Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609:622-629, 2022 Cited by PubMed: 35863378DOI: 10.1038/s41586-022-05116-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.01 Å) |
Structure validation
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