7U5P
CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH ACTIVIN-A
Summary for 7U5P
Entry DOI | 10.2210/pdb7u5p/pdb |
Descriptor | Activin receptor type-2A, Inhibin beta A chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | cell signaling, receptor-ligand complex, growth factor, receptor interaction, activin a, actriia, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 108955.52 |
Authors | Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E. (deposition date: 2022-03-02, release date: 2022-06-22, Last modification date: 2023-10-18) |
Primary citation | Chu, K.Y.,Malik, A.,Thamilselvan, V.,Martinez-Hackert, E. Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition. J.Biol.Chem., 298:102076-102076, 2022 Cited by PubMed: 35643319DOI: 10.1016/j.jbc.2022.102076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.14 Å) |
Structure validation
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