7TXD
Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9
Summary for 7TXD
Entry DOI | 10.2210/pdb7txd/pdb |
EMDB information | 26157 |
Descriptor | Envelope glycoprotein gp120, Envelope glycoprotein gp41, T-cell surface glycoprotein CD4, ... (9 entities in total) |
Functional Keywords | hiv, env, broadly neutralizing, darpin, cd4, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 358164.75 |
Authors | Cerutti, G.,Gorman, J.,Kwong, P.D.,Shapiro, L. (deposition date: 2022-02-08, release date: 2023-04-12, Last modification date: 2023-09-27) |
Primary citation | Glogl, M.,Friedrich, N.,Cerutti, G.,Lemmin, T.,Kwon, Y.D.,Gorman, J.,Maliqi, L.,Mittl, P.R.E.,Hesselman, M.C.,Schmidt, D.,Weber, J.,Foulkes, C.,Dingens, A.S.,Bylund, T.,Olia, A.S.,Verardi, R.,Reinberg, T.,Baumann, N.S.,Rusert, P.,Dreier, B.,Shapiro, L.,Kwong, P.D.,Pluckthun, A.,Trkola, A. Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30:1323-1336, 2023 Cited by PubMed: 37605043DOI: 10.1038/s41594-023-01062-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.87 Å) |
Structure validation
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