7TMC
TMEM106B singlet filament extracted from MSTD neurodegenerative human brain
Summary for 7TMC
Entry DOI | 10.2210/pdb7tmc/pdb |
EMDB information | 25995 |
Descriptor | Transmembrane protein 106B, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | tmem106b, tmem filament, mstd, neuropeptide |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 96123.45 |
Authors | Hoq, M.R.,Bharath, S.R.,Jiang, W. (deposition date: 2022-01-19, release date: 2023-01-25, Last modification date: 2023-11-22) |
Primary citation | Hoq, M.R.,Bharath, S.R.,Hallinan, G.I.,Fernandez, A.,Vago, F.S.,Ozcan, K.A.,Li, D.,Garringer, H.J.,Vidal, R.,Ghetti, B.,Jiang, W. Cross-beta helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia. Acta Neuropathol, 145:707-710, 2023 Cited by PubMed: 36952000DOI: 10.1007/s00401-023-02563-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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