7T6I
Crystal structure of HLA-DP1 in complex with pp65 peptide in reverse orientation
Summary for 7T6I
Entry DOI | 10.2210/pdb7t6i/pdb |
Descriptor | HLA class II histocompatibility antigen DP alpha chain, MHC class II antigen, pp65 peptide, ... (7 entities in total) |
Functional Keywords | antigen presentation, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 45847.97 |
Authors | Lim, J.J.,Reid, H.,Rossjohn, J. (deposition date: 2021-12-13, release date: 2022-12-07, Last modification date: 2023-10-25) |
Primary citation | Klobuch, S.,Lim, J.J.,van Balen, P.,Kester, M.G.D.,de Klerk, W.,de Ru, A.H.,Pothast, C.R.,Jedema, I.,Drijfhout, J.W.,Rossjohn, J.,Reid, H.H.,van Veelen, P.A.,Falkenburg, J.H.F.,Heemskerk, M.H.M. Human T cells recognize HLA-DP-bound peptides in two orientations. Proc.Natl.Acad.Sci.USA, 119:e2214331119-e2214331119, 2022 Cited by PubMed: 36442096DOI: 10.1073/pnas.2214331119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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