7T4Q
CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11
Summary for 7T4Q
Entry DOI | 10.2210/pdb7t4q/pdb |
EMDB information | 25685 |
Descriptor | Envelope glycoprotein H, Fab 13H11 heavy chain, Fab 13H11 light chain, ... (12 entities in total) |
Functional Keywords | human cytomegalovirus, glycoprotein complex, antibody complex, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human betaherpesvirus 5 More |
Total number of polymer chains | 11 |
Total formula weight | 340976.83 |
Authors | Kschonsak, M.,Johnson, M.C.,Schelling, R.,Green, E.M.,Rouge, L.,Ho, H.,Patel, N.,Kilic, C.,Kraft, E.,Arthur, C.P.,Rohou, A.L.,Comps-Agrar, L.,Martinez-Martin, N.,Perez, L.,Payandeh, J.,Ciferri, C. (deposition date: 2021-12-10, release date: 2022-03-23) |
Primary citation | Kschonsak, M.,Johnson, M.C.,Schelling, R.,Green, E.M.,Rouge, L.,Ho, H.,Patel, N.,Kilic, C.,Kraft, E.,Arthur, C.P.,Rohou, A.L.,Comps-Agrar, L.,Martinez-Martin, N.,Perez, L.,Payandeh, J.,Ciferri, C. Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8:eabm2536-eabm2536, 2022 Cited by PubMed: 35275719DOI: 10.1126/sciadv.abm2536 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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