7T0W
Complex of GABA-A synaptic receptor with autoimmune antibody Fab115
This is a non-PDB format compatible entry.
Summary for 7T0W
Entry DOI | 10.2210/pdb7t0w/pdb |
EMDB information | 25583 25585 |
Descriptor | Gamma-aminobutyric acid receptor subunit beta-2, Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit gamma-2, ... (8 entities in total) |
Functional Keywords | autoimmunity, encephalitis, gaba, inhibitory, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 307353.23 |
Authors | Noviello, C.M.,Hibbs, R.E.,Kreye, J.,Teng, J.,Pruss, H. (deposition date: 2021-11-30, release date: 2022-07-13, Last modification date: 2022-07-20) |
Primary citation | Noviello, C.M.,Kreye, J.,Teng, J.,Pruss, H.,Hibbs, R.E. Structural mechanisms of GABA A receptor autoimmune encephalitis. Cell, 185:2469-, 2022 Cited by PubMed: 35803245DOI: 10.1016/j.cell.2022.06.025 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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