7SQ8
Cryo-EM structure of mouse apo TRPML1 channel at 2.598 Angstrom resolution
Summary for 7SQ8
Entry DOI | 10.2210/pdb7sq8/pdb |
EMDB information | 25379 |
Descriptor | Mucolipin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... (4 entities in total) |
Functional Keywords | ion channel, membrane protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 4 |
Total formula weight | 264015.06 |
Authors | |
Primary citation | Gan, N.,Han, Y.,Zeng, W.,Wang, Y.,Xue, J.,Jiang, Y. Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P 2 and rapamycin. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 35131932DOI: 10.1073/pnas.2120404119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.598 Å) |
Structure validation
Download full validation report