7SMT
Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol
Summary for 7SMT
Entry DOI | 10.2210/pdb7smt/pdb |
EMDB information | 25202 25205 25206 25207 25208 |
Descriptor | Acetylcholine receptor subunit alpha, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | acetylcholine receptor, nicotinic receptor, torpedo, cys-loop receptor, ion channel, muscle-type nicotinic receptor, transport protein |
Biological source | Tetronarce californica (Pacific electric ray) More |
Total number of polymer chains | 5 |
Total formula weight | 278061.86 |
Authors | Rahman, M.M.,Basta, T.,Teng, J.,Lee, M.,Worrell, B.T.,Stowell, M.H.B.,Hibbs, R.E. (deposition date: 2021-10-26, release date: 2022-03-09, Last modification date: 2022-04-27) |
Primary citation | Rahman, M.M.,Basta, T.,Teng, J.,Lee, M.,Worrell, B.T.,Stowell, M.H.B.,Hibbs, R.E. Structural mechanism of muscle nicotinic receptor desensitization and block by curare. Nat.Struct.Mol.Biol., 29:386-394, 2022 Cited by PubMed: 35301478DOI: 10.1038/s41594-022-00737-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.56 Å) |
Structure validation
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