7RI1
Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120
Summary for 7RI1
Entry DOI | 10.2210/pdb7ri1/pdb |
Descriptor | Glycoprotein 120, Lamma VHH antibody J3, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | llama, antibody, vhh, hiv-1, gp120, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 2 |
Total formula weight | 58842.66 |
Authors | Zhou, T.,Kwong, P.D. (deposition date: 2021-07-19, release date: 2022-03-30, Last modification date: 2023-10-25) |
Primary citation | Zhou, T.,Chen, L.,Gorman, J.,Wang, S.,Kwon, Y.D.,Lin, B.C.,Louder, M.K.,Rawi, R.,Stancofski, E.D.,Yang, Y.,Zhang, B.,Quigley, A.F.,McCoy, L.E.,Rutten, L.,Verrips, T.,Weiss, R.A.,Doria-Rose, N.A.,Shapiro, L.,Kwong, P.D. Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30:862-875.e4, 2022 Cited by PubMed: 35413243DOI: 10.1016/j.str.2022.03.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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