7QOT
Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes
Summary for 7QOT
Entry DOI | 10.2210/pdb7qot/pdb |
Descriptor | Coagulation factor XIa heavy chain, Kininogen-1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | plasma kallikrein (pk), high molecular weight kininogen (hk), factor xii (fxii), factor xi (fxi), factor ix (fix), bradykinin (bk), blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 88082.52 |
Authors | Li, C.,Awital, B.,Wong, S.,Dreveny, I.,Meijers, J.,Emsley, J. (deposition date: 2021-12-28, release date: 2023-01-18, Last modification date: 2024-01-31) |
Primary citation | Li, C.,Voos, K.M.,Pathak, M.,Hall, G.,McCrae, K.R.,Dreveny, I.,Li, R.,Emsley, J. Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. J Thromb Haemost, 17:759-770, 2019 Cited by PubMed: 30801944DOI: 10.1111/jth.14418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.24 Å) |
Structure validation
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