7QDP
Crystal structure of FLT3 T343I in complex with the canonical ligand FL
Summary for 7QDP
Entry DOI | 10.2210/pdb7qdp/pdb |
Descriptor | Fms-related tyrosine kinase 3 ligand, Receptor-type tyrosine-protein kinase FLT3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | activation complex, complex, receptor tyrosine kinase, rtk-iii, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 334224.54 |
Authors | Pannecoucke, E.,Savvides, S.N. (deposition date: 2021-11-27, release date: 2022-12-14, Last modification date: 2024-01-31) |
Primary citation | Pannecoucke, E.,Savvides, S.N. Crystal structure of FLT3 T343I in complex with the canonical ligand FL To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.691 Å) |
Structure validation
Download full validation report