7Q1Y
X-ray structure of human A2ML1
Summary for 7Q1Y
Entry DOI | 10.2210/pdb7q1y/pdb |
Descriptor | Alpha-2-macroglobulin-like protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | protease inhibitor, thioester protein, a2m family, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 323344.91 |
Authors | Andersen, G.R.,Zarantonello, A.,Enghild, J.J.,Nielsen, N.S. (deposition date: 2021-10-22, release date: 2022-04-20, Last modification date: 2024-05-01) |
Primary citation | Nielsen, N.S.,Zarantonello, A.,Harwood, S.L.,Jensen, K.T.,Kjoge, K.,Thogersen, I.B.,Schauser, L.,Karlsen, J.L.,Andersen, G.R.,Enghild, J.J. Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family. Nat Commun, 13:3033-3033, 2022 Cited by PubMed: 35641520DOI: 10.1038/s41467-022-30758-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.4 Å) |
Structure validation
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