7P2D
Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
Summary for 7P2D
Entry DOI | 10.2210/pdb7p2d/pdb |
Related | 7NP9 |
Descriptor | Isoform 2 of Integrin alpha-M, Integrin beta, hCD11bNb1 nanobody, ... (6 entities in total) |
Functional Keywords | integrin receptor, complement, adhesion, phagocytosis, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 152830.30 |
Authors | Jensen, R.K.,Andersen, G.R. (deposition date: 2021-07-05, release date: 2022-05-04, Last modification date: 2024-01-31) |
Primary citation | Jensen, R.K.,Pedersen, H.,Lorentzen, J.,Laursen, N.S.,Vorup-Jensen, T.,Andersen, G.R. Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2. J.Biol.Chem., 298:102168-102168, 2022 Cited by PubMed: 35738398DOI: 10.1016/j.jbc.2022.102168 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report