7MJ5
complex of human thrombin with XC-43
Summary for 7MJ5
Entry DOI | 10.2210/pdb7mj5/pdb |
Descriptor | Putative secreted salivary protein, Thrombin light chain, Thrombin heavy chain, ... (6 entities in total) |
Functional Keywords | inhibitor, serine protease, flea, blood clotting |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 18 |
Total formula weight | 227929.36 |
Authors | Lu, S.,Tirloni, L.,Andersen, J.F. (deposition date: 2021-04-19, release date: 2021-12-22, Last modification date: 2023-10-18) |
Primary citation | Lu, S.,Tirloni, L.,Oliveira, M.B.,Bosio, C.F.,Nardone, G.A.,Zhang, Y.,Hinnebusch, B.J.,Ribeiro, J.M.,Andersen, J.F. Identification of a substrate-like cleavage-resistant thrombin inhibitor from the saliva of the flea Xenopsylla cheopis. J.Biol.Chem., 297:101322-101322, 2021 Cited by PubMed: 34688666DOI: 10.1016/j.jbc.2021.101322 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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