7LA4
Integrin AlphaIIbBeta3-PT25-2 Complex
Summary for 7LA4
Entry DOI | 10.2210/pdb7la4/pdb |
EMDB information | 23245 |
Descriptor | PT25-2 heavy chain, MAGNESIUM ION, PT25-2 light chain, ... (11 entities in total) |
Functional Keywords | pt25-2, cell adhesion |
Biological source | Mus musculus More |
Total number of polymer chains | 4 |
Total formula weight | 249590.66 |
Authors | Bush, M.W.,Walz, T.,Coller, B.,Filizola, M.,Spasic, A.,Nesic, D.,Li, J. (deposition date: 2021-01-05, release date: 2022-01-12, Last modification date: 2022-07-27) |
Primary citation | Nesic, D.,Bush, M.,Spasic, A.,Li, J.,Kamata, T.,Handa, M.,Filizola, M.,Walz, T.,Coller, B.S. Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding. Blood Adv, 5:1781-1790, 2021 Cited by PubMed: 33760023DOI: 10.1182/bloodadvances.2020004166 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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