7K8O

Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C002

Summary for 7K8O

Entry DOI	10.2210/pdb7k8o/pdb
Descriptor	C002 Fab Heavy Chain, C002 Fab Light Chain, GLYCEROL, ... (5 entities in total)
Functional Keywords	human neutralizing antibody, sars-cov-2, receptor binding domain, covid-19, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	49529.08
Authors	Jette, C.A.,Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-09-27, release date: 2020-10-21, Last modification date: 2023-10-18)
Primary citation	Barnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J. SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588:682-687, 2020 Cited by PubMed: 33045718 DOI: 10.1038/s41586-020-2852-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation