7BAG
C3b in complex with CP40
Summary for 7BAG
Entry DOI | 10.2210/pdb7bag/pdb |
Descriptor | Complement C3, Compstatin CP40, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | complement system, c3b, c3 convertase, inhibitor, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 178330.76 |
Authors | Lamers, C.,Xue, X.,Smiesko, M.,van Son, H.,Wagner, B.,Sfyroera, G.,Gros, P.,Lambris, J.,Ricklin, D. (deposition date: 2020-12-15, release date: 2022-01-12, Last modification date: 2024-02-07) |
Primary citation | Lamers, C.,Xue, X.,Smiesko, M.,van Son, H.,Wagner, B.,Berger, N.,Sfyroera, G.,Gros, P.,Lambris, J.D.,Ricklin, D. Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors. Nat Commun, 13:5519-5519, 2022 Cited by PubMed: 36127336DOI: 10.1038/s41467-022-33003-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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